The Chemical structure of Abaloparatide from Remetide company

Abaloparatide/247062-33-5 Drug Peptide

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Detail introduction: Abaloparatide/247062-33-5

The chemical formula of Abaloparatide
English name Abaloparatide
Chinese name 阿巴帕肽
CAS NO 247062-33-5
Peptide sequence Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-Aib-Lys-Leu-His-Thr-Ala-NH2
Molecular formula C174H300N56O49
Molecular weight 3960.5896
storage temperature 2-8℃
purity ≥98%
Package 1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement.
Product English synonyms

Introduction of Abaloparatide

Abaloparatide, whose Chinese name is 阿巴帕肽, is a new type of parathyroid hormone-related peptide (PTHrP) developed by Radius Health. It is a powerful and selective activator of PTH-I receptor, which can increase bone mineral content and bone mineral content. Density and bone strength promote bone formation. It was approved for marketing by the FDA on April 28, 2017, and its trade name is Tymlos.

The main role of Abaloparatide

Abaloparatide is injected subcutaneously for the treatment of osteoporosis in postmenopausal women who are at risk of fracture or are ineffective to other treatments and can effectively reduce the rate of new vertebral and non-vertebral fractures. Compared with teriparatide, Abaloparatide can better reduce the incidence of fracture and hypercalcemia.

Abaloparatide Usage and Synthetic Method

Preparation:

Abaloparatide is a polypeptide composed of 34 amino acid residue. The patent discloses the preparation method of Abapatide. First, three peptide resin fragments are synthesized by solid-phase synthesis, and then peptide fragments 2 and 3 are combined with peptide resin Fragment 1 is connected. However, this method requires a freeze-drying process before the condensation of peptide fragments 2 and 3, and the generation of peptide resin fragments 2 and 3 requires the use of a large amount of expensive 2-CTC resin, which leads to increased production costs.

Application of Abaloparatide:

Abaloparatide is a polypeptide composed of 34 amino acid residue. It is a new Chemicalbook parathyroid hormone-related peptide (PTHrP) developed by RadiusHealth. It is a powerful and selective activator of PTH-I receptors. It can increase bone mineral content, bone density, and bone strength, and promote bone formation.

How to buy Abaloparatide in the U. S.

Peptide supplier Remetide specializes in the production and sales of peptides in the USA, as well as Professional Drug peptide R&D. Feel free to contact us if you have any questions or inquiries about Abaloparatide Peptides.