Detail introduction: Dynorphin A (1-13)/DYNORPHIN A (HUMAN, 1-13) (PORCINE, RAT, BOVINE)/72957-38-1
| English name | Dynorphin A (1-13) |
| Chinese name | 强啡肽 A (1-13) |
| CAS NO | 72957-38-1 |
| Peptide sequence | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys |
| Molecular formula | C75H126N24O15 |
| Molecular weight | 1603.95 |
| storage temperature | 2-8℃ |
| purity | ≥98% |
| Package | 1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement. |
| Product English synonyms | DYNORPHIN A PORCINE FRAGMENT 1-13; DYNORPHIN A(HUMAN, 1-13); DYNORPHIN A (HUMAN, 1-13) (PORCINE, RAT, BOVINE) |
What’s Dynorphin A (1-13)?
Porcine dynorphin A(1-13) acetate is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+] I in individual neurons similar to increases seen with acute NMDA treatment.
In 1979, Goldstein et al. extracted a 17 peptide with extremely strong opioid activity from the pig pituitary and named it dynorphin. (nociceptin, orphanin-FQ, OFQ) and endomorphin (endomorphin, EM) are both endogenous opioid peptides [1].
Prodynorphin is the precursor of dynorphin, which is finally converted into neoendorphin, dynorphin A and dynorphin B in the body. Endogenous dynorphin has a variety of fragment structures, including Dyn1-32, 1-24, 1-17, 1-8, and 20-32, of which 1-17 is also called DynA, which is the main active fragment in the dynorphin family one
What is the role of Dynorphin？
Dynorphin has a strong analgesic effect, and its precursor is prodynorphin. Dynorphin (DYN) is another type of neuropeptide discovered in 1979 after enkephalin (ENK). In addition to participating in behavior regulation and analgesia, it can also pass through nerve or non-neural cells and has the same antibacterial peptide. Similar structure and physical and chemical properties.
How to buy Dynorphin A (1-13) in the U. S.
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