Detail introduction: Pasireotide/396091-73-9
English name | Pasireotide |
CAS NO | 396091-73-9 |
Peptide sequence | Cyclo[Hyp(2-aminoethylcarboxyl)-Phg-D-Trp-Lys-Tyr(Bzl)-Phe] |
Molecular formula | C58H66N10O9 |
Molecular weight | 1047.23 |
storage temperature | 2-8℃ |
purity | ≥98% |
Package | 1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement. |
Product English synonyms | Cyclo[(2S)-2-phenylglycyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-L-tyrosyl-L-phenylalanyl-(4R)-4-[[[(2-aminoethyl)amino]carbonyl]oxy]-L-prolyl];SOM230 |
Product description
Pasireotide (SOM230) is a long-acting cyclohexapeptide somatostatin analogue that can increase the agonist activity of somatostatin receptors. The pKi for sst1/2/3/4/5 are 8.2/9.0/ 9.1/<7.0/9.9. It can inhibit the secretion of GH, IGF-I and ACTH, and can be used to study acromegaly and Cushing’s disease. It also has antisecretory, antiproliferative and pro-apoptotic activities.
Signifor LAR (pasireotide) is a somatostatin analog.
Specific LAR is specifically indicated for the treatment of patients with acromegaly, whose response to surgery is insufficient and/or is not an option for surgery.
Signifor LAR is provided as an injection suspension for intramuscular injection. The FDA’s approval of Signifor LAR for acromegaly is based on two studies in two populations.
Side effects of Signifor LAR
The adverse effects associated with the use of Signifor LAR may include but are not limited to the following:
Diarrhea, gallstone disease, high blood sugar, diabetes
How to buy Pasireotide in the U. S.
Peptide supplier Remetide specializes in the production and sales of peptides in the USA, as well as Professional Drug peptide R&D. Feel free to contact us if you have any questions or inquiries about Pasireotide Peptides.