Introduction from Drug peptide supply about Decapeptide-12/Lumixyl/137665-91-9
| English name | Decapeptide-12 |
| Chinese name | 十肽-12 |
| CAS NO | 137665-91-9 |
| Peptide sequence | Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr |
| Molecular formula | C65H90N18O17 |
| Molecular weight | 1395.52 |
| storage temperature | 2-8℃ |
| purity | ≥98% |
| Package | 1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement. |
| Product English synonyms | lumixyl;L-Tyrosine, L-tyrosyl-L-arginyl-L-seryl-L-arginyl-L-lysyl-L-tyrosyl-L-seryl-L-seryl-L-tryptophyl- |
What is Decapeptide-12?
Decapeptide-12 is a cosmetic raw material that can inhibit the formation of melanin, lighten pigmentation, reduce pigmentation, even and brighten skin tone. It was developed by dermatology researchers at Stanford University. A new type of peptide with enzymatic activity (tyrosinase promotes the overproduction of melanin, which leads to uneven pigmentation, dark spots, etc.).
Application of decapeptide-12
Tyrosinase is an enzyme essential to the production of melanin and other pigments. A deficiency of tyrosinase results in type I oculocutaneous albinism while any mutation that causes tyrosinase to be overactive will lead to hyperpigmentation of the skin secondary to melanin production. Both the medical and cosmetics industries are interested in tyrosinase inhibitors, like decapeptide-12, as both therapeutics and to help better clarify how the enzyme cascade of pigment production works.
The food industry has also investigated decapeptide-12 as a potential preservative and flavor enhancer. Tyrosinase catalyzes the oxidation of phenolic compounds found in fruits and vegetables (it is what turns potatoes black after they are cut) to quinones. This conversion gives food an unpleasant taste and color. It also makes it harder for certain proteins to be digested and thus decreases the nutritional value of food.
Tyrosinase has a number of unique roles in the insect world. It can affect wound healing, parasite encapsulation, and the formation of an insect’s hard exosekleton. Inhibitors of tyrosinase, like decapeptide-12, have been studied as potential insecticides.
Tyrosinase has a unique dual catalytic function and is a key enzyme in melanin synthesis in vivo, which is closely related to human aging. Abnormal overexpression can lead to pigmentation diseases in the human body. Tyrosinase inhibitors can treat the currently common pigmented skin diseases such as freckles, chloasma, and senile plaques. Among the popular whitening cosmetics on the market, arbutin, vitamin C derivatives, kojic acid and its derivatives, green tea extract, licorice extract, and other traditional Chinese medicine extracts are all tyrosinase inhibitors, mainly by inhibiting the ability of tyrosinase to inhibit the synthesis of melanin, thereby exerting a whitening effect.
The mechanism of decapeptide-12 for beauty
Decapeptide 12 inhibits tyrosinase synthesis, thereby effectively (40%) reducing melanin production. It can maximally dilute chloasma, freckles, age spots, sun spots, uneven skin tone and light injury caused by excessive pigmentation. And Lumixyl Decapeptide 12 has no hydroquinone toxicity and side effects which some other whitening ingredients have, such as allergies, irritation, and redness.
How to buy Decapeptide-12 in the U. S.?
Remetide Peptide Supplier specializes in the production and sales of peptides in the USA, as well as Professional Drug peptide R&D. Feel free to contact us if you have any questions or inquiries about Peptides.
Hot line:+19498788363
Wechat:americhina
Email:amin@remetide.com