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Peptide-Fe complexes have been identified as promising iron-chelators[1], and peptide segments that change their conformation due to external stimuli have been used in peptide-based molecular devices[2]. Additionally, experiments modeling volcanic or hydrothermal settings have shown that amino acids can be converted into their peptides by use of coprecipitated (Ni,Fe)S and CO[3]. Finally, an Integrated Peptide and Protein prediction Framework based on Fused features and Ensemble models (IPPF-FE) has been proposed to precisely predict peptides[4]. Peptide-Fe complexes are formed mainly through the carboxyl and hydroxyl oxygen bond[1].

Ezatiostat (TER199, TLK199, Telintra)[1][2] is a peptidomimetic inhibitor of Glutathione S-transferase P1-1 (GSTP1-1)[2] and a tripeptide analog of glutathione[1]. It is being studied as a potential treatment for severe chronic neutropenia in clinical trials[3] and has been shown to stimulate the formation of bone marrow cells that are precursors to granulocytes and monocytes (white blood cells)[4][5]. It undergoes de-esterification to TLK235 and TLK236, which are its active forms[4]. Ezatiostat has a novel mechanism of action and beneficial effects on bone marrow[2][3]. It promotes maturation of hematopoietic

Pinealon is a synthetic peptide composed of three amino acids[1]. It has been shown to modify behavior and protect cells against the effects of aging[1]. Pinealon is available as a dietary supplement in capsule form[2] and has been found to have anabolic effects, improving the activity of the Central nervous system and other organs[3][4][5]. Pinealon is a dietary supplement with a synthesized brain peptide that normalizes the brain’s function by reducing its peptide deficiency and restoring balance[6]. It has been shown to be effective in reducing wrinkles

PT-141 is a peptide hormone that improves sexual function in both men and women by stimulating the MC-4R[1][2]. It is used as a medication to help with low sex drive and ED[3], and has been shown to be effective in clinical trials[4]. However, it is not yet approved by the FDA[5]. The most common side effects of PT 141 are nausea, vomiting, flushing, and headaches[6][7]. Other less common side effects include dizziness, stuffy nose, and tiredness[8][9]. PT-141 is a quick acting treatment option to help improve

Epitalon is a synthetic peptide, telomerase activator, and putative anti-aging drug[1][2]. It is a derivative of Epithalamin[2], which is naturally produced in the pineal gland[3]. Epitalon has the potential to modulate telomerase[2], the enzyme that maintains and protects the telomere[4][5]. Epitalon has a variety of benefits, including lengthening telomeres in human cells, promoting deeper sleep, delaying and preventing age-related diseases, and boosting energy levels[6][7]. Epitalon also helps to increase the body’s production of telomerase, an enzyme responsible for replicating DNA so that the body can repair

KPV is a peptide that is naturally produced in the body and is found in the hormone alpha-MSH[1]. It is a potent anti-inflammatory peptide[2] that has shown promise in treating a number of disease conditions, with the most active research being in the area of inflammatory bowel disease[2][3].  It is a relatively newer peptide that is being researched for a number of disease conditions[4]. KPV has been shown in studies to kill Candida albicans[5] and possesses anti-inflammatory properties; however, its mechanisms of action still remain unknown[6]. It is

Lunasin is a group of amino acids, called a peptide, found in soybeans, oats, barley, and other plants[1][2][3]. Research into the properties of lunasin began in 1996[4][3], with a focus on cancer, cholesterol, and inflammation[1][3]. A Lunasin regimen consists of LunaRich X capsules (12 per day) and Reliv NOW (a mixture of vitamins, minerals, and antioxidants)[5]. Lunasin is a peptide found in soy that has been shown to have antioxidant, anti-inflammatory, anticarcinogenic, and immune-modulating properties. It is taken orally for cancer, amyotrophic lateral sclerosis (ALS), high

BPC-157 is a synthetic peptide that has been investigated for its regenerative effects, particularly in rats suffering toxic or surgical trauma[1]. It has also been studied for its potential to treat inflammatory bowel disease and improve soft tissue healing[2]. Additionally, BPC-157 is believed to help alleviate joint pain, improve joint mobility, and boost recovery from injuries[3] , as well as increase vascular flow to the muscles[3]. It is derived from a specific protein found in the stomach and is often used to treat conditions and disorders in