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The Chemical structure of Somatostatin (CCRIS 3629)

Somatostatin/CCRIS 3629/51110-01-1

Detail intruduction:Somatostatin/CCRIS 3629/51110-01-1

Somatostatin/CCRIS 3629/Drug peptide

English nameSomatostatin
CAS NO51110-01-1
Peptide sequence
Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys(Cys3&Cys14 bridge)
Molecular formulaC76H104N18O19S2
Molecular weight1637.88
storage temperature2-8℃
purity≥98%
Package1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement.
Product English synonymsCCRIS 3629;SOMATOSTATIN [GIF];SOMATOSTATIN (HUMAN, OVINE, PORCINE, RAT, MOUSE)

What is Somatostatin?

Somatostatin is also called SS, SST or SOM. This growth hormone inhibitory hormone affects several areas of the body by hindering the secretion of other hormones.

Somatostatin is a hormone that many different tissues produce, but it is found primarily in the nervous and digestive systems. The primary function of somatostatin is to prevent the production of other hormones and also stop the unnatural rapid reproduction of cells — such as those that may occur in tumors. The hormone also acts as a neurotransmitter and has a role in the gastrointestinal tract.

What does Somatostatin do?

Somatostatin affects several areas of the body. In the hypothalamus, it regulates the secretion of hormones coming from the pituitary gland, including growth hormone and thyroid stimulating hormone. In the pancreas, somatostatin inhibits the secretion of pancreatic hormones, including glucagon and insulin. Finally, in the gastrointestinal tract, the hormone reduces gastric secretion and the emission of gastrointestinal hormones, such as secretin and gastrin.

Potential Problems with Somatostatin Inhibitor

Because it is an inhibitor, somatostatin is important to balance hormone levels in the body and stop the effects of over-production of certain hormones. That means that somatostatin levels that are too low can cause the problems associated with high levels of other hormones. Growth hormone, in particular, can be problematic. However, this is a rarely reported condition.

Instead, some patients will struggle with excessive somatostatin levels when they have a specific type of endocrine tumor called a somatostatinoma. This tumor produces the hormone independently. The end result is extreme suppression of the hormones normally inhibited by somatostatin, such as insulin, which can cause major health problems.

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