Introduction from Drug peptide supply about:β-Amyloid (1-40)/131438-79-4
| English name | β-Amyloid (1-40) |
| Chinese name | BETA淀粉样蛋白片段1-40 |
| CAS NO | 131438-79-4 |
| Peptide sequence | Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val |
| Molecular formula | C194H295N53O58S1 |
| Molecular weight | 4329.9 |
| storage temperature | 2-8℃ |
| purity | ≥98% |
| Package | 1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement. |
| Product English synonyms |
Introduction of Beta-Amyloid(1-40)
Aß (1-40) together with Aß (1-42) are two major C-terminal variants of the Aß protein constituting the majority of Aßs. These undergo post-secretory aggregation and deposition in the Alzheimer’s disease brain.
Mechanism of β-Amyloid (1-40)
Beta-amyloid (Aβ) peptides are derived from the amyloid precursor protein (APP), and the sequential proteolytic cleavage of APP by β- and γ-secretases generates distinct Aβ species. Aβ can aggregate to form soluble oligomeric species and insoluble fibrillar or amorphous assemblies. Certain forms of aggregated peptides are toxic to neurons. Alzheimer’s disease is characterized by the accumulation of aggregated Aβ peptides in senile plaques and vascular deposits.
How to buy β-Amyloid (1-40) in the U. S.
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