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Introduction from Drug peptide supply about:Angiotensin (1-7)/51833-78-4

chemical formula of Angiotensin (1-7)


English name Angiotensin (1-7)
Chinese name 血管紧张素 (1-7)
CAS NO 51833-78-4
Peptide sequence Asp-Arg-Val-Tyr-Ile-His-Pro
Molecular formula C41H62N12O11
Molecular weight 899
storage temperature 2-8℃
purity ≥98%
Package 1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement.
Product English synonyms angiotensinii(1-7;angiotensin fragment 1-7 human acetate;A779;(DES-PHE8) ANGIOTENSIN II;DRVYIHP

Introduction of Angiotensin1-7

Angtensin 1-7 is the main active component of renin-angiotensin system (RAS), which is produced by the decomposition of angiotensin II by angiotensin converting enzyme 2(ACE2). Angotensin1-7 inhibited the activity of purified canine angiotensin converting enzyme (ACE) with an IC50 of 0.65μM m. Angotensin1-7 can be used as a local synergistic modulator of kinin-induced vasodilation by inhibiting angiotensin-converting enzyme and releasing nitric oxide. Angiotensin1-7 blocks the proliferation and hypertrophy of smooth muscle cells induced by AngII, and shows anti-angiogenesis and growth inhibition effects on endothelium.



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