Introduction from Drug peptide supply about:Melittin/20449-79-0
| English name | Melittin |
| Chinese name | 蜂毒素 |
| CAS NO | 20449-79-0 |
| Peptide sequence | Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2 |
| Molecular formula | C131H229N39O31 |
| Molecular weight | 2846.5 |
| storage temperature | 2-8℃ |
| purity | ≥98% |
| Package | 1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement. |
| Product English synonyms | beevenommelittin;forapin;forapine;C11198;melittinfromhoneybeevenom |
Introduction of melittin
Mellitin : Also known as “a natural substitute for botulinum toxin”, it is a very good skin care raw material, it can stimulate the production of collagen in the skin, firm and lift, smooth fine lines and restore elasticity.
The mechanism of action of melittin
Mellittin is one of the substances with the strongest anti-inflammatory activity known to human beings. The anti-inflammatory activity is 100 times that of hydrocortisone. It can reduce the phosphorylation of proteins by inhibiting the activity of protein kinases, reducing the skin, blood vessels, and joints. , inflammatory effects of liver and neuronal tissue, with hormone-like effects, but no adverse effects of hormones. Mellitin can also effectively inhibit the growth of bacteria and reduce the damage of bacteria on the skin surface to the skin. Mellittin can act on the nervous system, selectively block N-acetylcholine receptors, affect the release of neurotransmitters, hinder muscle contraction, and prevent the formation of wrinkles and fine lines. .
The application of melittin
There are a variety of melittin peptides in melittin, which have strong penetrating power. Mellittin can inhibit the central nervous system under certain circumstances, paralyze the neural hemisphere cortex, and finally block the development of cholinergic nerves, effectively inhibiting neurological disease. It inhibits the excitatory conduction of the sympathetic ganglia of the autonomic nervous system, and enhances the activity and excitability of gastrointestinal smooth muscle; third, it inhibits the conduction of peripheral nerve impulses, hindering or delaying its conduction velocity. Mellitin has obvious hypotensive effect, and melittin also has positive frequency and negative inotropic effects on the myocardium. By inhibiting the generation of thromboplastin and prothrombin activator, and inhibiting the aggregation of platelets, the prethrombotic state can be eliminated, and it can be clinically used for the prevention and treatment of atherosclerosis and thrombosis. Mellittin has a direct hemolytic effect by disrupting the permeability of red blood cell membranes.
How to buy Melittin in the U. S.
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