Introduction from Drug peptide supply about:Calcitonin salmon/47931-85-1
| English name | Calcitonin salmon |
| Chinese name | 鲑降钙素 |
| CAS NO | 47931-85-1 |
| Peptide sequence | Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2(Cys1&Cys7 bridge) |
| Molecular formula | C145H240N44O48S2 |
| Molecular weight | 3431.85 |
| storage temperature | 2-8℃ |
| purity | ≥98% |
| Package | 1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement. |
| Product English synonyms | salmoncalcitonin-(i-32);salmoncalcitonini;tz-ct;Salmon Calcitonin Acetate;Salcatonin |
What is Salmon Calcitonin?
Salmon calcitonin, also known as salmon calcitonin, is a synthetic polypeptide preparation derived from salmon.
Pharmacological effects of salmon calcitonin
Salmon calcitonin significantly reduces bone calcium loss in high turnover bone diseases such as osteoporosis, deformed bone disease (Paget’s disease), painful neurodystrophy (Sudeck’s disease) and malignant osteolysis, the effect on the trunk bone of postmenopausal osteoporosis is more significant than that of the limb bone, and it is more significant on the high turnover bone disease than the low turnover bone disease. Salmon calcitonin can inhibit osteoclast activity while stimulating osteoblast formation and its activity, calcitonin can also increase urinary calcium, phosphorus and sodium excretion by inhibiting osteolysis and reducing renal tubular resorption, but serum calcitonin Calcium does not drop below the normal range.
Additional Information About Salmon Calcitonin
The drug also inhibits the secretory activity of the stomach and pancreas, but does not affect gastrointestinal motility. It has been proved that salmon calcitonin has analgesic effect on some patients with painful bone disease. All calcitonins are structurally similar, with a single chain of 32 amino acids in different arrangements. The amino acid order depends on the species, and their functions are basically the same. Among the 32 amino acids of salmon calcitonin and human calcitonin, 16 are different, but the effect and application of the two on Paget’s disease of bone are the same. The drug has a high affinity for its receptor binding sites present in certain regions of the central nervous system and has a longer duration of action than synthetic mammalian calcitonin.
How to buy Calcitonin salmonin the U. S.
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