The chemical structure of lecirelin drug peptide

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Introduction from Drug peptide supplier about: Lecirelin/61012-19-9

the chemical structure of LECIRELIN

 

English name Lecirelin
Chinese name 兰瑞肽
CAS NO 61012-19-9
Peptide sequence Glp-His-Trp-Ser-Tyr-Tle-Leu-Arg-Pro-NHEt
Molecular formula C59H84N16O12
Molecular weight 1209.42
storage temperature 2-8℃
purity ≥98%
Package 1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement.
Product English synonyms SUPERGESTRAN(TM);Lecirelin(6-(3-methyl-D-valine)-9-(N-ethyl-L-prolynamide)-10-deglycinamide);(DES-GLY10,TBU-D-GLY6,PRO-NHET9)-LHRH;(D-TLE6)-LEUPROLIDE;(D-TLE6)-LEUPRORELIN;[D-TLE6,PRO-NHET9]-LHRH

Somatostatin sustained-release preparations—lanreotide

Lanreotide is the first somatostatin sustained-release preparation that has been successfully developed. It is a new type of long-acting somatostatin (SM) octapeptide analog. of peptide inhibitors. Studies have shown that it may act mainly by binding to somatostatin receptors (SMRs), with a good affinity for peripheral (pituitary and pancreatic) SMRs and a weaker affinity for central receptors.

Main applications of lanreotide

Lanreotide is clinically used for the long-term treatment of patients with acromegaly who have not responded to surgery and radiation therapy. This new treatment modality reduces levels of certain hormones in the body, such as growth hormone or insulin-like growth factors.

Toxicology study

Like native somatostatin, lanreotide is a peptide inhibitor of many endocrine, neuroendocrine, exocrine and paracrine functions. It has good affinity for peripheral (pituitary and pancreatic) somatostatin receptors, but weaker affinity for central receptors. This feature makes it have a good specific effect on growth hormone secretion and digestive tract hormone secretion. Lanreotide is more active than natural somatostatin and has a longer duration of action. The inhibitory effect on growth hormone secretion has obvious selectivity compared with the inhibitory effect on insulin secretion, which makes the medicine suitable for treating acromegaly. On the other hand, the inhibitory effect of lanreotide on exocrine secretion, gastrointestinal hormones and cell proliferation mechanisms makes it very beneficial for symptomatic treatment of gastrointestinal endocrine tumors, especially carcinoid tumors.

How to buy Lecirelin in the U. S.

Remetide Peptide Supplier specializes in the production and sales of peptides in the USA, as well as Professional Drug peptide R&D. Feel free to contact us if you have any questions or inquiries about Lecirelin Peptides.

 

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