Detail intruduction：SYN-AKE/Dipeptide diaminobutyroyl benzylamide diacetate/823202-99-9
| English name | SYN-AKE/Dipeptide diaminobutyroyl benzylamide diacetate |
| CAS NO | 823202-99-9 |
| Peptide sequence | H-β-Ala-Pro-Dab-NHBzl.2AcOH |
| Molecular formula | C19H29N5O3.2(C2H4O2) |
| Molecular weight | 495.58 |
| storage temperature | 2-8℃ |
| purity | ≥98% |
| Package | 1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement. |
| Product English synonyms | (2S)-beta-Alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butanamide acetate;
SYN-AKE; snake-tripeptide; Snaketrip Chemical bookpetide; Dipeptide Diaminobutyroyl Benzylamide Diacetate; Snaketrippetide |
What is SYN-AKE (snake venom tripeptide)?
SYN-AKE (snake venom tripeptide) is a small peptide that mimics the activity of the snake venom toxin Waglerin I. Clinical trials have shown that the snake venom peptide can reduce the production of wrinkles by inhibiting muscle contraction, and has excellent smoothing and rapid wrinkle removal properties.
What is the mechanism of action of SYN-AKE (snake venom tripeptide)?
AKE (Snake Venom Tripeptide) acts as an effective smoothing and anti-wrinkle active product by relaxing facial muscles. The action mode of this active tripeptide is consistent with the neuromuscular blocking compound Waglerin 1 of Temple Viper venom. AKE (snake venom tripeptide) acts on the postsynaptic membrane and is a reversible antagonist of muscle nicotinic acetylcholine receptor (nmAChR). AKE (snake venom-like tripeptide) binds to the epsilon subunit of nmAChR to block the binding of acetylcholine to the receptor and ultimately leads to the blocking of the receptor. In the blocked state, sodium ions cannot be taken in, and it cannot be depolarized. The nerve excitation transmission is blocked. The muscles relax as a result.
Clinical test of SYN-AKE (snake venom tripeptide)
Experiments on cultured muscle cells showed that the use of 250PPM AKE (snake venom tripeptide) reduced the muscle contraction rate by 36% after one minute and 82% after two hours. Therefore, snake venom peptide can be used as an instant wrinkle removal product. AKE (snake venom tripeptide) anti-wrinkle determination
Fifty subjects participated in this experiment. AKE (Snake Venom Tripeptide) was compared with placebo and reference substances. Both products used recommended concentrations. The test lasted for 28 days, twice a day. The results show that AKE (snake venom tripeptide) can significantly reduce the expression lines on the forehead, and AKE (snake venom tripeptide) has significantly higher activity than the reference substance acetyl hexapeptide-8.
Introduction to Snake Venom Serum Protein-like Peptides
Snake venom-like serum protein-like peptide, also known as SYN-AKE or tripeptide, is a small peptide that mimics the activity of the snake venom toxin Waglerin I, which is found in the venom of the Temple Viper viper (Tripidolaemus wagleri).
SYN-AKE is a synthetic tripeptide derivative and a new snake venom-like active compound and is a muscle nicotinic acetylcholine receptor (nmAChR) antagonist. The main components of snake venom-like serum protein-like peptide (SYN-AKE) are: water (25-50%), glycerin, glycerin (Glycerin) contains about 50%, dipeptide and dipeptide-2 (Dipeptide Diaminobutyroyl Benzylamide Diacetate) ) Contains 0.1%-1%.
These ingredients can effectively improve the texture of the skin, make the skin smooth and delicate, enhance the complexion, can penetrate into the deep layers of the skin, replenish the collagen lost over time, and eliminate the traces left by the years ~ wrinkles.
It can also regulate nerve conduction signals, inhibit fine lines and other aging phenomena, relax skin cells that are constantly tense during the day, thereby increasing vitality, allowing cells to restore elasticity, allowing the skin to have firmness and anti-wrinkle, regenerate a firm V-shaped face, and restore The performance of the skin’s youthful state.
How to buy SYN-AKE (snake venom tripeptide) in U.S.
Remetide Peptide Supplier specializes in the production and sales of peptides in the USA, as well as Professional Drug peptide R&D. Feel free to contact us if you have any questions or inquiries about SYN-AKE Peptides.