Detail introduction: Ganirelix/123246-29-7
English name | Ganirelix/Ganirelix acetate |
Chinese name | 加尼瑞克 |
CAS NO | 123246-29-7 |
Peptide sequence | Ac-D2Nal-DCpa-DPal-Ser-Tyr-DHar(Et2)-Leu-Har(Et2)-Pro-DAla-NH2 |
Molecular formula | C80H113ClN18O13 |
Molecular weight | 1570.34 |
storage temperature | 2-8℃ |
purity | ≥98% |
Package | 1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement. |
Product English synonyms | Ganirelixum;ganirelix Acetate |
Introduction of Ganirelix
The full name of Ganirelix is Ganirelix Acetate Injection, Ganirelix is developed and produced by Merck. In 2013, it was approved for listing in China by the State Food and Drug Administration of China.
It is a gonadotropin-releasing hormone (GnRH) antagonist, a synthetic decapeptide, and has a high antagonistic activity to naturally-produced gonadotropin-releasing hormone (GnRH). Competitive
Ingredients of Ganirelix
The active ingredient Ganirelix (INN) is a synthetic decapeptide, which has a high antagonistic activity to the naturally-occurring gonadotropin-releasing hormone (GnRH).
The following peptide formula is formed by replacing the amino acids at positions 1, 2, 3, 6, 8, and 10 of natural GnRH.
Chemical name: N-acetyl-3-(2-naphthalene)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridine)-D-alanyl-L-serine Acyl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysine Acyl-L-prolyl-D-alaninamide acetate b
Ganirelix acetate is the “stabilizer” of the IVF antagonist program
Which has a high antagonistic activity to the naturally produced gonadotropin-releasing hormone. The effect of ganirelix acetate is more obvious, and it is often used in women who do control ovarian stimulation programs for IVF.
In other words, taking ganirelix acetate during IVF treatment can help women to better promote the discharge, so as to obtain more dominant follicles in the later period.
Patients who use antagonist programs to promote ovulation usually start using ovulation-stimulating drugs during menstruation. In order to avoid premature ovulation before ovulation is completed, It acetate will be added at this time to prevent the premature appearance of luteinizing hormone. Prevent ovulation.
In addition to preventing premature ovulation, has the following two effects in the antagonist program: avoiding ovarian hyperstimulation syndrome and reducing the burden of treatment
How to buy Ganirelix in the U. S.
Remetide peptide biotechnology company specializes in the production and sales of peptides in the USA, as well as Professional Drug peptide R&D. Feel free to contact us if you have any questions or inquiries about Ganirelix Peptides.