Detail introduction: LL-37/Cathelicidin LL 37 (human)/154947-66-7
| English name | LL-37 |
| CAS NO | 154947-66-7 |
| Peptide sequence | Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser |
| Molecular formula | C205H340N60O53 |
| Molecular weight | |
| storage temperature | 2-8℃ |
| purity | ≥98% |
| Package | 1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement. |
| Product English synonyms | Cathelicidin LL 37 (human); Antibacterial Protein LL-37 (human) |
Introduction of Antibacterial Protein LL-37 (human)
The human body mainly produces two types of antimicrobial peptides: defensin family peptides and cathelicidin family peptides.
Although the defensin family of peptides has many members, cathelicidin has only one antimicrobial peptide product LL-37. It s the C-terminal cleavage product of cathelicidin peptide Hcap-18, which can directly kill bacteria, fungi, and viruses.
What is the function of LL-37?
LL-37 plays an immunomodulatory role by chemotaxis of immune cells, regulating the secretion of inflammatory promoters/inhibitors, and coordinating natural immunity and acquired immunity.
It can also act on vascular endothelial cells and epithelial cells to stimulate angiogenesis and promote damage repair. In addition, the uncontrolled expression of LL-37 can cause a variety of diseases. For example, in psoriasis, the increased expression of LL-37 may promote the autoimmune response.
How to buy Cathelicidin LL 37 in the U. S.
Remetide Peptide Supplier specializes in the production and sales of peptides in the USA, as well as Professional Drug peptide R&D. Feel free to contact us if you have any questions or inquiries about Cathelicidin LL 37 Peptides.