Introduction to peptide synthesis services
What is peptide synthesis service？
Peptide synthesis is also called a synthetic peptide. It is a solid-phase synthesis sequence generally from the C terminal (carboxyl terminal) to the N terminal (amino terminal) synthesis. In the past, peptide synthesis was carried out in a solution called liquid phase synthesis. Since Merrifield successfully developed the solid-phase peptide synthesis method in 1963
after continuous improvement and perfection, the solid-phase method has become a common technique in peptide and protein synthesis today, showing the incomparable advantages of the classic liquid-phase synthesis method. , Thereby greatly reducing the difficulty of product purification at each step. Peptide synthesis is generally divided into two types: solid-phase synthesis and liquid-phase peptide synthesis.
Polypeptide is a biologically active substance-related to various cell functions in the organism. Its molecular structure is between amino acids and proteins. It is a compound composed of multiple amino acids combined by peptide bonds in a certain sequence.
Polypeptide is a general term for biologically active substances related to various cell functions in organisms and is often used in functional analysis, antibody research, especially drug development, and other fields.
Methods of peptide synthesis
Peptide synthesis is a solid-phase synthesis sequence, generally from the C-terminal (carboxyl terminal) to the N-terminal (amino terminal). In the past, peptide synthesis was carried out in a solution called liquid phase synthesis.
Since Merrifield successfully developed the solid-phase peptide synthesis method in 1963, after continuous improvement and perfection, the solid-phase method has become a common technique in peptide and protein synthesis today, showing the incomparable advantages of the classic liquid-phase synthesis method. , Thereby greatly reducing the difficulty of product purification at each step. Peptide synthesis is generally divided into two types: solid-phase synthesis and liquid-phase peptide synthesis.
Peptide synthesis consists of the following cycles
1. Deprotection: Fmoc-protected columns and monomers must use an alkaline solvent (piperidine) to remove the amino protective group.
2. Activation and cross-linking: The carboxyl group of the next amino acid is activated by an activator. The activated monomer reacts with the free amino group to form a peptide bond. In this step, a large amount of super-concentration reagents are used to drive the reaction to completion. Circulation: The two-step reaction repeatedly circulates until the synthesis is completed.
3. Elution and deprotection: The peptide is eluted from the column, and its protecting group is eluted and deprotected by a deprotection agent (TFA).
Remetide’s peptide product synthesis service
The Remetide peptide biotechnology company has been focusing on the research and development of peptides for many years and has very rich experience in peptide synthesis.
We provide services including peptide customization, peptide modification, catalog peptides, cosmetic peptide synthesis, and peptide library construction to meet the needs of scientific research in different fields.
Products include amino acid derivatives, peptide reagents, small molecule compounds, ELISA kits, etc.
At present, it has independent peptide research and development center and a 1,000 square meter sterile laboratory in Hangzhou, China. It has an internationally advanced peptide separation and purification system, equipped with advanced reactors, automatic purifiers, automatic freeze-drying systems, ultraviolet spectrophotometers and other special precision instruments, and has a complete peptide production line
Remetide has its own laboratories and production workshops in North America, Asia Pacific, and Europe: Hong Kong and other places. Remetide can provide high-quality services for global scientific research users. We can provide peptide synthesis and purification services from milligrams to grams, and competitive prices to meet customer needs.
How to contact us to purchase Peptide Synthesis Service in the USA
Hot line:19498788363(Mr. Yao)
WeChat:americhina
Email: amin@remetide.com
